Admissible design options between Minimax and Optimal

Lists the admissible design options between

Usage

twostage.admissible(x)

Arguments

x

output from ph2simon call

Value

twostage.admissible returns design options that are admissible (Jung et al, 2004). The output is a matrix with 8 columns: r1, n1, r, n, EN(p0), PET(p0), qLo, qHi. The columns qLo and qHi give the range of probability values for which the particular design is admissible.

References

Jung SH, Lee T, Kim K, and George, SL. (2004). Admissible two-stage designs for phase II cancer clinical trials. Statistics in medicine 23(4), 561-569.

Examples

  oo = ph2simon(0.5, 0.7, 0.05, 0.1)
  twostage.admissible(oo)
#>            r1 n1  r  n   EN(p0)   PET(p0)   qLo   qHi
#> Minimax    14 27 32 53 36.11440 0.6494460 0.285 1.000
#> Admissible 12 23 34 57 34.51987 0.6611803 0.112 0.285
#> Optimal    13 24 36 61 34.01324 0.7293719 0.000 0.112